28. June - 1. July 2012
12th International symposium on MPS and related diseases
Noordwijkerhout, The Netherlands

Patient program

Thursday 28. June 2012
15:00
Registration
17:00 Words of Welcome
Hanka Meutgeert, chair of the Dutch patient and family organization for metabolic disorders
Ans van der Ploeg & Frits Wijburg, on behalf of the scientific committee
17:15
     
Regenerative medicine: promises for future treatment
Christine Mummery, the Netherlands
18:30 Welcome reception
Snack & Drinks

Friday 29. June 2012

Theme: Musculoskeletal disease and Mucopolysaccharidoses
09:00
Session 1 - scientific & patient program
Bones and joints: defining the problem
Chairs: Calogera Simonaro & Michael Beck
09:00
The patient’s story - short movie
09:05
     
General overview of bone and cartilage tissue; growth and metabolism en clinical issues
Ans van de Ploeg & Arnold Reuser,
the Netherlands
09:35
     
Challenges in treating musculoskeletal disease in MPSs
Katherine Ponder, USA

10:00

Practical approaches to musculoskeletal disease in MPSs
Bianca Link, Germany



10:30
Coffee break


11:00
Theme: Getting to know each other; our stories - patient program
11:00
Group meetings for different disorders


12:30
Lunch



Theme: The central nervous system (CNS) and Mucopolysaccharidoses
13:30
Session 3 - scientific & patient program
The Brain in MPSs and other LSDs: defining the problems and approaches for therapy
Chairs: Roberto Giugliani & Frits Wijburg
13:30
The patient’s story - Short movie
13:35
     
Overview of CNS disease in MPS
Maurizio Scarpa, Italy
14:05
    
Challenges in treating the brain in MPSs
David Begley, United Kingdom
14:30
Emerging gene therapy strategies for lysosomal storage diseases
Beverly Davidson, USA


15:00
Tea break


15:30
Family session 2: Meeting the care needs for patients and families
Chairs: Barbara Wedehase & Simon Jones
15:30
      
A coordinated approach to patient care in the hospital;: Specialized center or not?
Lorne Clarke, Canada

15:45
      
A Canadian perspective of specialized health care services
Kirsten Harkins, Canada
16:00
       
The role of the Nurse Specialist in LSD’s (Lysosomal storage disorders)
Jean Mercer, United Kingdom
16:15
       
Facing transition
Fredi Wiesbauer, MPS dad, Switzerland
16:30
      
Developing a best practice model of transition in the UK
Chris Hendriksz,United Kingdom

16:45
Forum discussion


17:15
Drinks & snacks & poster walks


Saturday 30. June 2012
09:00 Session 5 - scientific & patient program
Novel approaches for treatment and early diagnosis
Chairs: George Ruiter & John Hopwood
09:00
     
Intrathecal enzyme therapy for MPS II and III
Joseph Muenzer, USA
09:20
     
Genistein: results of clinical trials
Frits Wijburg, the Netherlands
09:40
    
Genistein: animal studies and a new trial
Brian Bigger, United Kingdom
10:00
    
Animal models and innovative therapies for brain disease
Kim Hemsley, Australia
10:20
General discussion


10:30
Coffee break


11:00
Family session 3: Living with MPS: challenges and possibilities
Chairs: Christine Lavery & Michel Beck
11:00
     
Through teenage years and out the other side
Jibreel Arshad, United Kingdom


11:10
     
Outdoor sports: hiking with MPS in Norway!
Kjersti Hagen, MPS I Mum, Norway
11:20 
      
Challenges of employment
Sophie Thomas, MPS society UK, United Kingdom
11:30
Managing the needs of children with progressive neurological diseases
Julie and Chris Kembrey, United Kingdom
11:40
    
Empowerment: patients in charge of decision making
Kimberly Frye, psychologist and MPS mum, USA
11:50
    
Giving birth and raising a child
Tamara Schiedon, the Netherlands


12:30
Lunch


13:30
Session 7 - scientific & patient program
Drug pricing and access to treatment
Chairs: Ans van de Ploeg & Alasdair Parker
13:30
    
Orphan drug development: successes and challenges
Bert Leufkens, the Netherlands
13:50
   
Perspectives of patients and families
Christine Lavery, United Kingdom
14:10
The doctor’s perspective
Carla Hollak, the Netherlands
14:30
    
Perspective of regulating authorities
Wim Goettsch, the Netherlands
14:50
      
Cost effectiveness and orphan drugs
Michael Schlander, Germany


15:10
General discussion


15:30
Tea break


16:00
Session 8 - scientific & patient program
Updates on treatment outcomes
Chairs: Maurizio Scarpa & David Begley
16:00
    
MPS I
Roberto Giugliani, Brazil
16:15
    
MPS II
Michael Beck, Germany
16:30
    
MPS IV
Chris Hendriksz, United Kingdom
16:45
    
MPS VI
Vassili Valayannopoulos, France
Oral presentations
17:00
Anti-idursulfase Antibody and the Efficacy of Enzyme Replacement Therapy in Mucopolysaccharidosis Type II Patients
Akemi Tanaka, Japan
17:10
Long-term Experience with Enzyme Replacement Therapy (ERT) in MPS II Patients with a Severe (Neuronopathic) Phenotype: an International Case Series
Christina Lampe, Germany
17:20 International multicenter study to identify predictors of long term outcome of Hurler syndrome patients after successful hematopoietic stem cell transplantation
Jaap Jan Boelens, the Netherlands
17:30
 
Lysosomal storage, neurodegeneration and brain inflammation in the mouse model of MPS III type C
Alexey Pshezhetsky, Canada


17:40
Drinks & snacks & poster walks


19:00
Congress dinner


Sunday 1. July 2012
09:00
     
MPS 2012 lectureMPSs: experiences from the past and lessons for the future
scientific & patient program

John Hopwood, Australia
09:40
Short break


09:45
Theme: How to deal with MPS related clinical issues and surgery - patient program
Chairs: Anna Tylki & Kirsten Harkins
09:45
    
Spinal cord compression
Bianca Link, Germany
10:00
      
Approaches to behavior management
Simon Jones, United Kingdom 
10:15
    
Anesthesia and MPS
Ian Bruce, United Kingdom 
10:30
     
Carpal tunnel syndrome
Steven Hovius, the Netherlands
10:45
     
High risk surgery: we had no choice
Michaela Weigl, MPS IV mum, Austria


11:00
Coffee break


11:30
Poster prizes
11:50
Presentation MPS 2013
International Symposium - Brazil
12:00
Closing remarks and farewell
12:15
End of the meeting